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Combining knowledge to cure HIV

Investigating the causes of HIV latency

- last updated: 01.07.2022

Investigating the causes of HIV latency

We use cutting edge molecular biology tools to elucidate the molecular mechanisms that contribute to HIV latency. We apply our fundamental biological findings to identify candidate novel targets for therapeutic intervention.

Papers and/or related content

Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency Allele-specific long-distance regulation dictates IL-32 isoform switching and mediates susceptibility to HIV-1 Catchet-MS identifies IKZF1-targeting Thalidomide analogues as novel HIV-1 latency reversal agents A two-color haploid genetic screen identifies novel host factors involved in HIV latency

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